We report the case of a 52-year-old man with a history of acute myeloid leukemia who presented to the emergency room with fatigue, dyspnea and chest pain. An unusual case of pulmonary granulocytic sarcoma treated with combined chemotherapy and radiation Vishwanath Sathyanarayanan1, Nagesh Taterao Sirsath1, Um Upon occasion, granulocytic sarcoma can actually appear as the initial manifestation of a myeloproliferative state. Granulocytic sarcoma, an uncommon solid, extra-medullary tumor is a rare presentation of acute myeloid leukemia. Myeloid sarcoma may arise before, concurrent with, or after the diagnosis of AML, chronic myelogenous leukemia (CML), or myelodysplastic syndrome (MDS) is made. Pulmonary granulocytic sarcoma (chloroma) mimicking an opportunistic infection in a patient with acute myeloid leukemia. Pui MH, Fletcher BD, Langston JW. 1. Acute Myelogenous Leukemia; Chloroma; Granulocytic Sarcoma; Heart . The authors declare no conflict of interest. imaging findings is broad and includes lymphoma and sarcomas [32]. A 36-year-old woman presented with cough, pleural effusion and atelectasis. Pulmonary granulocytic sarcoma (chloroma) mimicking an opportunistic infection in a patient with acute myeloid leukemia . Pulmonary granulocytic sarcoma (chloroma) mimicking an opportunistic infection in a patient with acute myeloid leukemia. 1-3 We herein describe a child who was seen with bilateral orbital tumors that were the initial manifestation of AML. Granulocytic Sarcoma is also known as myeloid sarcoma, chloroma, extramedullary myeloblastoma, and extramedullary myeloid tumor. A systemic review of imaging findings in chloroma is presented here (Table 1) along with site-specific common differential considerations. Radiology images. 7. Acute myeloid leukemia (AML) can involve the orbit as a solid tumor termed myeloid sarcoma or chloroma. Central nervous system chloroma: a 12-year-old male of acute myeloid leukaemia presented with scalp swelling, headache and seizures. Figure 1. The imaging appearance of mediastinal granulocytic sarcomas is not specific with a wide differential diagnosis including lymphoma, thymoma, teratoma, infection/mediastinitis/abscess and haematoma. Granulocytic sarcoma, also known as chloroma or extramedullary myeloblastoma, is a rare solid tumor composed of primitive precursors of the granulocytic series of wbc. Pulmonary granulocytic sarcoma (chloroma) mimicking an opportunistic infection in a patient with acute myeloid leukemia. In some patients, calcification and sequestered bone fragments are seen as well. Guimaraes in 2013 reported a case of pulmonary granulocytic sarcoma mimicking an opportunistic infection in a patient with acute myeloid leukaemia. It was formerly known as granulocytic sarcoma, chloroma, or myeloblastoma. This patient developed pleural and pulmonary involvement by primary granulocytic sarcoma. Marcos D. Guimarães, Edson Marchiori, Edith M. Marom, Mark J. Routbort, Myrna C. B. Godoy, Pulmonary granulocytic sarcoma (chloroma) mimicking an opportunistic infection in a patient with acute myeloid leukemia, Annals of Hematology, 10.1007/s00277-013-1768-3, 93, 2, (327-328), (2013). (Chest 1988; 94:655-56) The imaging revealed the presence of a cardiac infiltrative mass involving the heart’s right free wall that proved to be a chloroma. [Google Scholar] 29 . The purpose of this study was to elucidate clinical and imaging features of MS based upon a multicenter patient sample. Takasugi JE, Godwin JD, Marglin SI, Petersdorf SH. A CT was requested to rule out pulmonary embolism. Radiology. RANULOCYTIC SARCOMA (or chloroma) has at- tracted considerable attention because of its close association with the various myeloproliferative dis- orders,' most often acute or chronic leukemia. Granulocytic sarcoma (chloroma) is an unusual extramedullary manifestation of acute myelogenous leukemia, chronic myelogenous leukemia, and the myeloproliferative syndrome. doi: 10.1097/MPH.0000000000001085. Prognostic factors. Hermann G, , Feldman F, , Abdelwahab IF, , Klein MJ. Chloroma is a rare, malignant tumor made up of granulocyte precursor cells. In this case, if the blurring effect of respiration is properly evaluated, the roentgen diagnosis of a tuberculous process was illogical. A myeloid sarcoma (chloroma, granulocytic sarcoma,: 744 extramedullary myeloid tumor), is a solid tumor composed of immature white blood cells called myeloblasts.A chloroma is an extramedullary manifestation of acute myeloid leukemia; in other words, it is a solid collection of leukemic cells occurring outside of the bone marrow ( subperiosteal ) and perineural involvement is uncommon tumor termed myeloid sarcoma ( ). Em, Routbort MJ, Godoy MCB was illogical orbit as a solid tumor myeloid! 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